ECONAZOLE BASE

Econazole base is an imidazole antifungal that disrupts ergosterol synthesis in fungal cell membranes. It is effective against dermatophytes and yeasts. Side effects include mild burning, redness, or irritation at the application site.

SKU: 9002c47d4f88 Category: Tag:

Product Description


Mechanism of Action

Econazole is an imidazole antifungal that inhibits fungal cytochrome P450‑dependent 14‑α‑demethylase, blocking conversion of lanosterol to ergosterol. This disrupts cell‑membrane synthesis, increasing permeability and causing fungal death. It is active against dermatophytes, yeasts and some molds.

Benefits and Advantages

Used in fungal‑cell‑membrane research, azole‑mechanism assays, ergosterol‑biosynthesis modelling, and antifungal‑resistance studies.

Side Effects and Risks

Risks include local irritation, burning, erythema, contact dermatitis and rare systemic absorption effects. Handle with azole‑antifungal precautions.

Datasheet


Molecular Formula

C18H15Cl3N2O

Molecular Weight

381.68 g/mol

CAS Number

27220-47-9

Storage Condition

Store in a cool, dry place; protect from light

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

econazole; 27220-47-9; Econazolum; Econazol; (+-)-Econazole

IUPAC/Chemical Name

1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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