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Product Description
Mechanism of Action
Dyphylline is a xanthine bronchodilator that increases intracellular cAMP by inhibiting phosphodiesterase. It relaxes bronchial smooth muscle but with significantly reduced CNS and cardiac stimulation compared with theophylline due to structural modifications that limit adenosine‑receptor antagonism.
Benefits and Advantages
Used in airway‑reactivity modelling, PDE‑inhibition studies, bronchodilator SAR research, and respiratory‑pharmacology assays.
Side Effects and Risks
Risks include mild tachycardia, GI upset, restlessness and tremor. Handle with xanthine‑derivative precautions.
Datasheet
| Molecular Formula | C10H14N4O4 |
|---|---|
| Molecular Weight | 254.24 g/mol |
| CAS Number | 479-18-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | dyphylline; Diprophylline; 479-18-5; Diphylline; 7-(2,3-Dihydroxypropyl)theophylline |
| IUPAC/Chemical Name | 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione |
| InChl Key | KSCFJBIXMNOVSH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3 |
| References |
3D Conformer.
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