About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Doxycycline hydrochloride is a tetracycline‑class antibiotic that binds the 30S ribosomal subunit, preventing aminoacyl‑tRNA attachment and inhibiting bacterial protein synthesis. Its lipophilicity confers broad tissue distribution and activity against intracellular bacteria.
Benefits and Advantages
Used in protein‑translation inhibition studies, intracellular pathogen modelling, MMP‑inhibition assays, and broad‑spectrum antimicrobial mechanism investigations.
Side Effects and Risks
Risks include photosensitivity, GI irritation, esophageal erosion, hepatotoxicity and interaction with calcium‑containing products. Handle with tetracycline‑compound precautions.
Datasheet
| Molecular Formula | C22H24N2O8·HCl |
|---|---|
| Molecular Weight | 480.9 g/mol |
| CAS Number | 10592-13-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Doxycycline hydrochloride; 10592-13-9; Doxycycline HCl; Doxigalumicina; Biocamycin |
| IUPAC/Chemical Name | (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride |
| InChl Key | PTNZGHXUZDHMIQ-CVHRZJFOSA-N |
| InChl Code | InChI=1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31);1H/t7-,10+,14+,15-,17-,22-;/m0./s1 |
| References |
3D Conformer.
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