DESCICLOVIR
Desciclovir is an antiviral prodrug metabolized to penciclovir, inhibiting viral DNA polymerase and slowing herpesvirus replication. Benefits include reduced duration and severity of outbreaks. Side effects include headache, nausea, and mild GI discomfort. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Desciclovir is the prodrug of penciclovir, converting through firstpass metabolism into the active antiviral compound. Penciclovir is a guanosine analogue phosphorylated intracellularly to its triphosphate form, which inhibits viral DNA polymerase and terminates replication in herpesviruses.
Benefits and Advantages
Used in viralreplication modelling, nucleosideanalogue SAR research, herpesvirus polymerase assays, drugactivation metabolism studies and antiviralmechanism investigations.
Side Effects and Risks
Risks include headache, GI upset, rash and rare hematologic effects. Handle with antiviralcompound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C8H11N5O2 |
|---|---|
| Molecular Weight | 209.21 g/mol |
| CAS Number | 84408-37-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | DESCICLOVIR; 84408-37-7; 6-Deoxyacyclovir; 2-[(2-aminopurin-9-yl)methoxy]ethanol; Desciclovirum |
| IUPAC/Chemical Name | 2-[(2-aminopurin-9-yl)methoxy]ethanol |
| InChl Key | OKQHSIGMOWQUIK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H11N5O2/c9-8-10-3-6-7(12-8)13(4-11-6)5-15-2-1-14/h3-4,14H,1-2,5H2,(H2,9,10,12) |
| References |
3D Conformer.
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