CYTIDINE
Cytarabine (ara‑C) is a DNA polymerase inhibitor used in leukemia. Side effects include myelosuppression, rash, and neurotoxicity at high doses.
About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cytidine is a pyrimidine nucleoside composed of cytosine linked to a ribose sugar. It serves as a fundamental building block of RNA and a precursor for cytidine triphosphate (CTP), which participates in phospholipid synthesis and RNA polymerization. Cytidine and its deoxy forms are also central to epigenetic regulation via cytosine methylation and demethylation cycles.
Benefits and Advantages
Used in nucleotide‑metabolism research, RNA‑synthesis studies, phospholipid‑biosynthesis modelling, epigenetic‑pathway analyses, and nucleoside‑transport investigations. It is also used as a reference substrate in kinase and deaminase enzyme assays.
Side Effects and Risks
Risks include minimal toxicity at research doses, but high concentrations may disrupt nucleotide balance and cellular metabolism. Handle as a low‑hazard biochemical with standard lab precautions.
Datasheet
| Molecular Formula | C9H13N3O5 |
|---|---|
| Molecular Weight | 243.22 g/mol |
| CAS Number | 65-46-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | greater than or equal to 100 mg/mL at 63 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | cytidine; 65-46-3; Cytosine riboside; 1-beta-D-Ribofuranosylcytosine; 4-Amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone |
| IUPAC/Chemical Name | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| InChl Key | UHDGCWIWMRVCDJ-XVFCMESISA-N |
| InChl Code | InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
