CROMOLYN SODIUM
Cromolyn sodium stabilizes mast cells and prevents mediator release, used in asthma and allergic disorders. Side effects include throat irritation and cough. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Cromolyn sodium is a mastcell stabilizer that prevents degranulation by blocking chloridechanneldependent calcium influx. This inhibits release of histamine, leukotrienes and other inflammatory mediators. It does not act as an antihistamine, but rather prevents upstream mediator release by stabilizing the mastcell membrane.
Benefits and Advantages
Used in allergypathway modelling, mastcell activation research, asthmainflammation studies, mediatorrelease assays and mucosal immunology investigations.
Side Effects and Risks
Risks include cough, throat irritation, mild bronchospasm and rare hypersensitivity. Handle with respiratoryagent precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C23H14Na2O11 |
|---|---|
| Molecular Weight | 512.3 g/mol |
| CAS Number | 15826-37-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | CROMOLYN SODIUM; 15826-37-6; Sodium cromoglycate; Disodium cromoglycate; sodium cromoglicate |
| IUPAC/Chemical Name | disodium;5-[3-(2-carboxylato-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate |
| InChl Key | VLARUOGDXDTHEH-UHFFFAOYSA-L |
| InChl Code | InChI=1S/C23H16O11.2Na/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;/q;2*+1/p-2 |
| References |
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