CROMOLYN SODIUM

Cromolyn sodium stabilizes mast cells and prevents mediator release, used in asthma and allergic disorders. Side effects include throat irritation and cough. Only GMP materials will be supplied, logistics all according to GDP.

SKU: d8b16c4ef337 Category: Tag:

Product Description


Mechanism of Action

Cromolyn sodium is a mastcell stabilizer that prevents degranulation by blocking chloridechanneldependent calcium influx. This inhibits release of histamine, leukotrienes and other inflammatory mediators. It does not act as an antihistamine, but rather prevents upstream mediator release by stabilizing the mastcell membrane.

Benefits and Advantages

Used in allergypathway modelling, mastcell activation research, asthmainflammation studies, mediatorrelease assays and mucosal immunology investigations.

Side Effects and Risks

Risks include cough, throat irritation, mild bronchospasm and rare hypersensitivity. Handle with respiratoryagent precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C23H14Na2O11

Molecular Weight

512.3 g/mol

CAS Number

15826-37-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

CROMOLYN SODIUM; 15826-37-6; Sodium cromoglycate; Disodium cromoglycate; sodium cromoglicate

IUPAC/Chemical Name

disodium;5-[3-(2-carboxylato-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate

InChl Key

VLARUOGDXDTHEH-UHFFFAOYSA-L

InChl Code

InChI=1S/C23H16O11.2Na/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;/q;2*+1/p-2

References

https://pubchem.ncbi.nlm.nih.gov/compound/27503;

3D Conformer.

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