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Product Description
Mechanism of Action
Clopamide is a thiazide‑like diuretic that inhibits the Na⁺/Cl⁻ symporter (NCC) in the distal convoluted tubule, increasing sodium, chloride and water excretion. It also reduces peripheral vascular resistance with chronic use.
Benefits and Advantages
Used in electrolyte‑transport studies, diuretic‑pharmacology research, antihypertensive‑mechanism modelling and renal‑function pathway experiments.
Side Effects and Risks
Risks include hypokalemia, hyponatremia, hyperuricemia, hypotension and metabolic disturbances. Handle with diuretic‑class safety guidelines.
Datasheet
| Molecular Formula | C12H16ClN3O3S2 |
|---|---|
| Molecular Weight | 345.8 g/mol |
| CAS Number | 636-54-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | clopamide; 636-54-4; Clopamidum; Clopamida; Aquex |
| IUPAC/Chemical Name | 4-chloro-N-[(2S,6R)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide |
| InChl Key | LBXHRAWDUMTPSE-AOOOYVTPSA-N |
| InChl Code | InChI=1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+ |
| References |
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