CLOFOCTOL
Clofoctol is an antibacterial agent disrupting bacterial membrane function. Side effects include cough irritation and GI upset. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Clofoctol is a bacteriostatic antibacterial agent that disrupts bacterial protein synthesis by interacting with ribosomal subunits and impairing mRNA translation efficiency. It accumulates in lung and bronchial tissues, making it useful in respiratorypathogen research. Clofoctol also modulates endoplasmicreticulum (ER) stress signalling and may induce UPRmediated apoptosis in selected cellular models.
Benefits and Advantages
Used in respiratorypathogen modelling (*S. pneumoniae*, *H. influenzae*), ERstress pathway studies, proteintranslation research, intracellular drugaccumulation assays and membraneinteraction investigations.
Side Effects and Risks
Risks include GI discomfort, allergic reactions, hepatic enzyme elevations and drowsiness. Handle with antibacterialagent precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H27ClO |
|---|---|
| Molecular Weight | 365.3 g/mol |
| CAS Number | 37693-01-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | clofoctol; 37693-01-9; Octofene; Clofoctolum; 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol |
| IUPAC/Chemical Name | 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol |
| InChl Key | HQVZOORKDNCGCK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H26Cl2O/c1-20(2,3)13-21(4,5)16-7-9-19(24)15(11-16)10-14-6-8-17(22)12-18(14)23/h6-9,11-12,24H,10,13H2,1-5H3 |
| References |
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