CLINDAMYCIN HYDROCHLORID
Clindamycin hydrochloride inhibits bacterial protein synthesis, treating anaerobic and grampositive infections. Side effects include diarrhea, C. difficile risk, and rash. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Clindamycin hydrochloride is a lincosamide antibiotic that binds the 50S ribosomal subunit and inhibits peptidechain elongation. It has excellent penetration into bone and anaerobic tissues. Effective against grampositive cocci and anaerobes.
Benefits and Advantages
Used in anaerobicbacteriology studies, ribosometarget modelling, osteomyelitis research, toxinsuppression studies (e.g., Streptococcal and Staphylococcal toxins) and intracellular pathogen assays.
Side Effects and Risks
Risks include C. difficile overgrowth, diarrhea, rash, hepatotoxicity and neutropenia. Handle as a potent proteinsynthesis inhibitor.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H34ClN3O5S |
|---|---|
| Molecular Weight | 424.0 g/mol |
| CAS Number | 21462-39-5 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | SureCN722402; RefChem:1099296; (2S,4R)-N-(2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl)-1-methyl-4-propyl-pyrrolidine-2-carboxamide;hydrochloride; Dalacin (TN); AC1LCVGH |
| IUPAC/Chemical Name | Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propylpyrrolidin-2-yl)thio-L-threo-α-D-galacto-octopyranoside hydrochloride |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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