CITALOPRAM
Citalopram is an SSRI that increases serotonin levels by inhibiting its reuptake. Used for depression and anxiety disorders, it offers mood stabilization and improved emotional balance. Side effects include nausea, insomnia, and sexual dysfunction. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Citalopram is a selective serotonin reuptake inhibitor (SSRI) that blocks the serotonin transporter (SERT), increasing synaptic serotonin levels. It enhances serotonergic neurotransmission in cortical and limbic circuits, modulating mood, anxiety and affective processing. It has minimal affinity for other neurotransmitter receptors.
Benefits and Advantages
Used in SERT-binding studies, SSRI pharmacology research, mood-disorder modelling, synaptic-plasticity experiments and drugdrug interaction studies via CYP2C19 metabolism.
Side Effects and Risks
Risks include nausea, insomnia, QT prolongation (dose-dependent), sexual dysfunction, serotonin syndrome and withdrawal reactions. Handle with CNS-modulating compound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C20H21FN2O |
|---|---|
| Molecular Weight | 324.4 g/mol |
| CAS Number | 59729-33-8 |
| Storage Condition | Store at 20 °C to 25 °C (68 °F to 77 °F); excursions permitted from 15 °C to 30 °C (59 °F to 86 °F). |
| Solubility | Sparingly soluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | citalopram; 59729-33-8; Nitalapram; Cipram; Citalopramum |
| IUPAC/Chemical Name | 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile |
| InChl Key | WSEQXVZVJXJVFP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 |
| References |
3D Conformer.
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