About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cisapride monohydrate is a prokinetic agent that enhances acetylcholine release in the enteric nervous system via 5-HT₄ receptor agonism and inhibits 5-HT₃-mediated reflex inhibition. This accelerates gastric emptying and increases lower-esophageal sphincter tone. It does not significantly block dopamine receptors.
Benefits and Advantages
Used in GI-motility research, serotonergic signalling studies, enteric-neuron modelling, gastroparesis research and prokinetic drug-development assays.
Side Effects and Risks
Risks include QT prolongation, arrhythmias (torsades de pointes), diarrhea, abdominal cramping and drug–drug interactions via CYP3A4. Handle with cardiac-safety precautions.
Datasheet
| Molecular Formula | C23H29ClFN4O5 |
|---|---|
| Molecular Weight | 498.95 g/mol |
| CAS Number | 76479-27-3 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide monohydrate |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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