CIMETROPIUM BROMIDE
Cimetropium bromide is an anticholinergic reducing GI motility and secretions, used for IBS and abdominal cramps. Side effects include dry mouth, blurred vision, and constipation. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Cimetropium bromide is a quaternary ammonium antimuscarinic agent that blocks M muscarinic receptors on smooth muscle. This reduces gastric motility, intestinal spasms and secretions. Due to poor bloodbrain barrier penetration, it primarily acts peripherally without strong CNS effects.
Benefits and Advantages
Used in GIspasm research, muscarinicreceptor pharmacology, smoothmuscle contractility studies, anticholinergic SAR investigations and functional boweldisorder modelling.
Side Effects and Risks
Risks include dry mouth, constipation, blurred vision, urinary retention and tachycardia. Handle using antimuscarinicagent precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H38BrNO5 |
|---|---|
| Molecular Weight | 438.4 g/mol |
| CAS Number | 51598-60-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cimetropium Bromide; Cimetropium (Bromide); Bromuro de cimetropio; Alginor; Bromure de cimetropium |
| IUPAC/Chemical Name | [(1R,2R,4S,5S)-9-(cyclopropylmethyl)-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate bromide |
| InChl Key | WDURTRGFUGAJHA-HNHWXVNLSA-M |
| InChl Code | InChI=1S/C21H28NO4.BrH/c1-22(11-13-7-8-13)17-9-15(10-18(22)20-19(17)26-20)25-21(24)16(12-23)14-5-3-2-4-6-14;/h2-6,13,15-20,23H,7-12H2,1H3;1H/q+1;/p-1/t15?,16-,17-,18+,19-,20+,22?;/m1./s1 |
| References | PubChem; ChemBL; FDA; |
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