About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cimetidine base is the nonsalt form of cimetidine with identical Hreceptor antagonism. It competitively blocks histaminedriven gastric acid secretion and possesses significant CYP450inhibitory activity. The base form is used in formulation chemistry and lipophilicity studies.
Benefits and Advantages
Used in pharmaceuticalsalt comparison studies, solubility testing, Hreceptor mechanism modelling, CYPinteraction assays and medicinalchemistry optimisation experiments.
Side Effects and Risks
Risks mirror standard cimetidine: hormonedisruption effects, CNS alterations, hepatic changes and major druginteraction potential. Handle with Hantagonist precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C10H16N6S |
|---|---|
| Molecular Weight | 252.34 g/mol |
| CAS Number | 51481-61-9 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | cimetidine; 51481-61-9; Ulcedin; Eureceptor; Gastromet |
| IUPAC/Chemical Name | N''-cyano-N-methyl-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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