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Product Description
Mechanism of Action
Chlorprothixene is a typical antipsychotic of the thioxanthene class that antagonises dopamine D₂ receptors in the brain, reducing dopaminergic transmission in the mesolimbic pathway. It also antagonises H₁, muscarinic and α₁-adrenergic receptors, producing sedation, anxiolysis and hypotension.
Benefits and Advantages
Used in psychosis-modelling studies, dopamine-receptor pharmacology, behavioural-sedation studies, multi-receptor binding analysis, and antipsychotic SAR profiling. Its mixed receptor activity makes it useful in broad-spectrum CNS-effect modelling.
Side Effects and Risks
Risks include sedation, anticholinergic effects, orthostatic hypotension, extrapyramidal symptoms and metabolic disturbances. Handle as a CNS-active antipsychotic.
Datasheet
| Molecular Formula | C18H18ClNS |
|---|---|
| Molecular Weight | 331.86 g/mol |
| CAS Number | 113-59-7 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | DTXSID30859205; 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine; 4695-61-8; RefChem:1066509; DTXCID60809677 |
| IUPAC/Chemical Name | 3-(9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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