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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Product Description
Mechanism of Action
Chlorphenoxamine is a diphenyl ether–derived H₁-antihistamine with strong anticholinergic and antispasmodic activity. It blocks H₁ receptors and muscarinic receptors, reducing allergic symptoms while also diminishing smooth-muscle contractions in the GI and respiratory tract. Its central nervous system penetration produces mild sedative effects.
Benefits and Advantages
Used in H₁-antihistamine pharmacology research, anticholinergic-pathway modelling, smooth-muscle inhibition studies, motion-sickness research and behavioural pharmacology evaluations. Serves as a reference compound in multi-target antihistamine studies.
Side Effects and Risks
Risks include sedation, blurred vision, tachycardia, dry mouth, urinary retention, constipation and impaired psychomotor function. Handle using anticholinergic-compound precautions.
Datasheet
| Molecular Formula | C18H22ClNO2 |
|---|---|
| Molecular Weight | 303.8 g/mol |
| CAS Number | 77-38-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Chlorphenoxamine; 77-38-3; Contristamine; Clorfenoxamina; Clorfenossamina |
| IUPAC/Chemical Name | 2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine |
| InChl Key | KKHPNPMTPORSQE-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H22ClNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3 |
| References |
3D Conformer.
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