CHLORCYCLYCINE
Chlorcyclizine is an antihistamine blocking H1 receptors to relieve allergy symptoms and motion sickness. Benefits include reduced itching and nasal symptoms. Side effects include drowsiness, dry mouth, and dizziness. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Chlorcyclizine is a firstgeneration Hantihistamine with anticholinergic and antiemetic properties. It competitively blocks H receptors, reducing histaminemediated vascular permeability, pruritus and allergic responses. Its ability to cross the bloodbrain barrier produces sedative and antimotionsickness effects.
Benefits and Advantages
Used in allergypathway research, histaminereceptor pharmacology, CNSpenetrant antihistamine studies, antiemetic modelling, and motionsickness mechanism investigations.
Side Effects and Risks
Risks include sedation, cognitive impairment, anticholinergic effects (dry mouth, urinary retention), tachycardia and dizziness. Handle as a CNSactive firstgeneration antihistamine.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H21ClN2 |
|---|---|
| Molecular Weight | 300.83 g/mol |
| CAS Number | 535-66-6 |
| Storage Condition | Store in a cool, dry place; protected from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | 1-[(4-chlorophenyl)(phenyl)methyl]piperazine |
| InChl Key | RRMCXSIOQJGLRO-UHFFFAOYSA-N |
| References | PubChem; ChemBL; FDA substance registry; |
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