CETHEXONIUM BROMIDE

Cethexonium bromide is a ganglionic blocker reducing blood pressure. Side effects include constipation, dry mouth, and orthostatic hypotension.

SKU: 4be30e9ac5cb Category: Tag:

Product Description


Mechanism of Action

Cethexonium bromide is a quaternary ammonium compound functioning as a ganglionic blocker. It inhibits nicotinic acetylcholine receptors in autonomic ganglia, reducing sympathetic and parasympathetic transmission. This leads to decreased vascular tone, reduced GI motility and modulation of smooth‑muscle activity.

Benefits and Advantages

Used in autonomic‑nervous‑system research, nicotinic‑receptor pharmacology, smooth‑muscle inhibition assays, pre‑ganglionic neurotransmission modelling and early antihypertensive drug‑mechanism investigations.

Side Effects and Risks

Risks include severe hypotension, urinary retention, paralytic ileus, blurred vision, tachycardia, and autonomic instability. Handle as a potent ganglionic blocker under strict lab controls.

Datasheet


Molecular Formula

C21H46BrNO

Molecular Weight

448.6 g/mol

CAS Number

1794-74-7

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Cethexonium bromide; 1794-74-7; F3T95WRD7W; BACTYL; MONOSEPT

IUPAC/Chemical Name

hexadecyl-(2-hydroxycyclohexyl)-dimethylazanium bromide

InChl Key

MFLMYFVIROLIRS-UHFFFAOYSA-M

InChl Code

InChI=1S/C24H50NO.BrH/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22-25(2,3)23-20-17-18-21-24(23)26;/h23-24,26H,4-22H2,1-3H3;1H/q+1;/p-1

References

https://pubchem.ncbi.nlm.nih.gov/compound/3083735;

3D Conformer.

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