CETHEXONIUM BROMIDE
Cethexonium bromide is a ganglionic blocker reducing blood pressure. Side effects include constipation, dry mouth, and orthostatic hypotension.
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Product Description
Mechanism of Action
Cethexonium bromide is a quaternary ammonium compound functioning as a ganglionic blocker. It inhibits nicotinic acetylcholine receptors in autonomic ganglia, reducing sympathetic and parasympathetic transmission. This leads to decreased vascular tone, reduced GI motility and modulation of smooth‑muscle activity.
Benefits and Advantages
Used in autonomic‑nervous‑system research, nicotinic‑receptor pharmacology, smooth‑muscle inhibition assays, pre‑ganglionic neurotransmission modelling and early antihypertensive drug‑mechanism investigations.
Side Effects and Risks
Risks include severe hypotension, urinary retention, paralytic ileus, blurred vision, tachycardia, and autonomic instability. Handle as a potent ganglionic blocker under strict lab controls.
Datasheet
| Molecular Formula | C21H46BrNO |
|---|---|
| Molecular Weight | 448.6 g/mol |
| CAS Number | 1794-74-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cethexonium bromide; 1794-74-7; F3T95WRD7W; BACTYL; MONOSEPT |
| IUPAC/Chemical Name | hexadecyl-(2-hydroxycyclohexyl)-dimethylazanium bromide |
| InChl Key | MFLMYFVIROLIRS-UHFFFAOYSA-M |
| InChl Code | InChI=1S/C24H50NO.BrH/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22-25(2,3)23-20-17-18-21-24(23)26;/h23-24,26H,4-22H2,1-3H3;1H/q+1;/p-1 |
| References |
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