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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cephalexin monohydrate is a first‑generation oral cephalosporin that inhibits bacterial cell‑wall synthesis through high‑affinity binding to PBPs, blocking transpeptidation of peptidoglycan chains. The monohydrate form ensures stability and predictable oral absorption. Strong activity is seen against gram‑positive cocci and certain gram‑negative bacilli.
Benefits and Advantages
Used in gram‑positive susceptibility profiling, β‑lactam SAR research, staphylococcal cell‑wall studies, oral PK modelling, biofilm‑growth inhibition assays and early‑generation cephalosporin mechanistic comparisons.
Side Effects and Risks
Risks include hypersensitivity, GI irritation, candidal overgrowth, rare renal inflammation and potential cross‑reactivity in penicillin‑allergic subjects. Handle under β‑lactam containment standards.
Datasheet
| Molecular Formula | C16H17N3O4S·H2O |
|---|---|
| Molecular Weight | 365.4 g/mol |
| CAS Number | 23325-78-2 |
| Storage Condition | Cephalexin capsules, tablets, and powder for oral suspension should be stored in tight containers at a temperature less than 40 °C, preferably between 15-30 °C. After reconstitution, cephalexin oral suspensions should be stored at 2-8 °C and discarded if not used within 2 wk. |
| Solubility | 10mg/mL |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cephalexin monohydrate; 23325-78-2; cefalexin hydrate; 7-(D-alpha-Amino-alpha-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid monohydrate; CHEBI:3535 |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate |
| InChl Key | AVGYWQBCYZHHPN-CYJZLJNKSA-N |
| InChl Code | InChI=1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15-;/m1./s1 |
| References |
3D Conformer.
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