About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Product Description
Mechanism of action
Cefixime is an oral third-generation cephalosporin that binds PBPs and inhibits cell-wall peptidoglycan synthesis in gram-negative and select gram-positive bacteria. It is stable to many β-lactamases and demonstrates strong activity against Enterobacteriaceae and respiratory pathogens.
Benefits and advantages
Used in UTI models, sexually transmitted infection research (e.g., *Neisseria gonorrhoeae*), respiratory-pathogen susceptibility studies, PK/PD simulations and community-resistance-trend monitoring. Serves as a reference for oral third-generation cephalosporins.
Side effects and risks
Risks include GI upset, allergic reactions, rare pseudomembranous colitis and possible alteration of gut microbiota. Handle with standard β-lactam antimicrobial precautions.
Datasheet
| Molecular Formula | C16H15N5O7S2 |
|---|---|
| Molecular Weight | 453.5 g/mol |
| CAS Number | 79350-37-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | CEFIXIME; 79350-37-1; Cefspan; Cephoral; Cefixima |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | OKBVVJOGVLARMR-QSWIMTSFSA-N |
| InChl Code | InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1 |
| References |
3D Conformer.
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