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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Carbasalate calcium is a calciumsalt complex of acetylsalicylic acid and urea designed to enhance gastric tolerability. After administration it rapidly decomposes into salicylic acid and acetylsalicylic acid, inhibiting cyclooxygenase1 and 2 (COX1/COX2) to block prostaglandin synthesis, reduce inflammation and inhibit platelet aggregation.
Benefits and advantages
Used in COXenzyme research, antiplatelet models, antiinflammatory pathway studies, pharmacokinetic solubility comparisons and analgesicmechanism profiling. Also used in acidsensitive tissue models where reduced gastric irritation is required.
Side effects and risks
Risks include bleeding tendencies, hypersensitivity, GI upset, renal effects and platelet dysfunction. Handle under NSAID and salicylate safety protocols.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C14H19CaNO8 |
|---|---|
| Molecular Weight | 458.4 g/mol |
| CAS Number | 66988-73-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | CARBASPIRIN CALCIUM; Calcium carbaspirin; N667F17JP1; DTXSID90206099; carbosalate calcium |
| IUPAC/Chemical Name | calcium;bis(2-acetyloxybenzoate);urea |
| InChl Key | VYMUGTALCSPLDM-UHFFFAOYSA-L |
| InChl Code | InChI=1S/2C9H8O4.CH4N2O.Ca/c2*1-6(10)13-8-5-3-2-4-7(8)9(11)12;2-1(3)4;/h2*2-5H,1H3,(H,11,12);(H4,2,3,4);/q;;;+2/p-2 |
| References |
3D Conformer.
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