BUTRIPTYLINE HCL
Butriptyline is a tricyclic antidepressant affecting serotonin and norepinephrine. Side effects include dry mouth, sedation, weight gain, and orthostatic hypotension. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Butriptyline is a tricyclic antidepressant (TCA) structurally related to amitriptyline but acting primarily as a serotonin reuptake inhibitor with weaker noradrenergic activity. It also antagonises muscarinic, histamine H and -adrenergic receptors, contributing to its sedative and anxiolytic properties.
Benefits and advantages
Used in depression-model research, serotonergicnoradrenergic interaction studies, TCA SAR profiling, receptor-binding assays and central-nervous-system behavioural pharmacology.
Side effects and risks
Risks include anticholinergic symptoms, QT prolongation, sedation, weight gain, cardiovascular effects and seizure risk at high doses. Handle with CNS-active and cardiotoxic-compound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H28ClN |
|---|---|
| Molecular Weight | 329.9 g/mol |
| CAS Number | 5585-73-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Butriptyline hydrochloride; 5585-73-9; Evadene; Butriptyline HCl; AY-62014 |
| IUPAC/Chemical Name | N,N,2-trimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)propan-1-amine;hydrochloride |
| InChl Key | MCWAFEJHLHEFOD-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H27N.ClH/c1-16(15-22(2)3)14-21-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)21;/h4-11,16,21H,12-15H2,1-3H3;1H |
| References |
3D Conformer.
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