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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent structurally related to atovaquone. It inhibits the mitochondrial electron transport chain, targeting the cytochrome bc₁ complex in protozoal pathogens, leading to ATP depletion and cell death.
Benefits and advantages
Used in protozoal-infection research, mitochondrial-electron-transport studies, veterinary-pharmacology modelling, quinone-antiprotozoal SAR studies and drug-resistance analyses.
Side effects and risks
Risks include hepatotoxicity, GI discomfort, hypersensitivity and photosensitivity. Handle under antimicrobial and quinone-compound safety protocols.
Datasheet
| Molecular Formula | C22H28O3 |
|---|---|
| Molecular Weight | 326.4 g/mol |
| CAS Number | 88426-33-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Buparvaquone; 88426-33-9; Butalex; Buparvacuona; Buparvaquonum |
| IUPAC/Chemical Name | 3-[(4-tert-butylcyclohexyl)methyl]-4-hydroxynaphthalene-1,2-dione |
| InChl Key | NEGDTWQGGLJCTL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,22H,8-12H2,1-3H3 |
| References |
3D Conformer.
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