About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Bunazosin is an α₁-adrenergic receptor antagonist that relaxes vascular smooth muscle, reducing peripheral vascular resistance and blood pressure. In ophthalmic use, bunazosin enhances aqueous-humor outflow by relaxing trabecular meshwork smooth muscle.
Benefits and advantages
Used in adrenergic-signalling research, glaucoma-mechanism studies, vascular-tone modelling, smooth-muscle physiology assays and α₁-receptor SAR investigations.
Side effects and risks
Risks include hypotension, dizziness, syncope, fatigue and mild tachycardia. Handle with adrenergic-antagonist precautions.
Datasheet
| Molecular Formula | C19H27N5O3 |
|---|---|
| Molecular Weight | 373.4 g/mol |
| CAS Number | 80755-51-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Bunazosin; 80755-51-7; Bunazosina; Bunazosine; Bunazosinum |
| IUPAC/Chemical Name | 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,4-diazepan-1-yl]butan-1-one |
| InChl Key | RHLJLALHBZGAFM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H27N5O3/c1-4-6-17(25)23-7-5-8-24(10-9-23)19-21-14-12-16(27-3)15(26-2)11-13(14)18(20)22-19/h11-12H,4-10H2,1-3H3,(H2,20,21,22) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
