BROMPERIDOL

Bromperidol is a highpotency antipsychotic blocking dopamine D2 receptors, used in schizophrenia. Side effects include extrapyramidal symptoms, rigidity, and restlessness. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 31577b6a6ef3 Category: Tag:

Product Description


Mechanism of action

Bromperidol is a highly potent butyrophenone antipsychotic that strongly antagonises dopamine D receptors, producing robust antipsychotic and anti-agitation effects. It also interacts with D, 5HT and adrenergic receptors, contributing to its pharmacological profile.

Benefits and advantages

Used in psychiatricpharmacology research, dopaminereceptor binding studies, EPSmodel development, highpotency neuroleptic SAR analysis and CNSbehavioural pharmacology.

Side effects and risks

Risks include profound extrapyramidal symptoms, dysphoria, QT prolongation, neuroleptic malignant syndrome, sedation and endocrine disturbances. Handle with highpotency neuroleptic safety precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C21H23BrFNO2

Molecular Weight

420.3 g/mol

CAS Number

10457-90-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

bromperidol; 10457-90-6; Impromen; Bromoperidol; 4-(4-(4-bromophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one

IUPAC/Chemical Name

4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

InChl Key

RKLNONIVDFXQRX-UHFFFAOYSA-N

InChl Code

InChI=1S/C21H23BrFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/2448;

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download