BROMOPRIDE
Bromopride is a prokinetic dopamine antagonist enhancing gastric motility and reducing nausea. Side effects include drowsiness, EPS, and diarrhea.
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Product Description
Mechanism of action
Bromopride is a dopamine D₂‑receptor antagonist structurally similar to metoclopramide. It increases gastrointestinal motility by removing dopaminergic inhibition of cholinergic activity in the enteric nervous system and enhances gastric emptying and lower‑oesophageal‑sphincter tone.
Benefits and advantages
Used in GI‑motility research, D₂‑receptor pharmacology, antiemetic‑mechanism modelling, prokinetic‑agent development and enteric neuroscience studies.
Side effects and risks
Risks include extrapyramidal symptoms, dystonia, hyperprolactinaemia, sedation, QT prolongation and GI distress. Handle with dopamine‑antagonist safety precautions.
Datasheet
| Molecular Formula | C14H22BrN3O2 |
|---|---|
| Molecular Weight | 344.25 g/mol |
| CAS Number | 4093-35-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | bromopride; 4093-35-0; Bromoprida; Bromopridum; Movipride |
| IUPAC/Chemical Name | 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide |
| InChl Key | GIYAQDDTCWHPPL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C14H22BrN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) |
| References |
3D Conformer.
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