About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Bifonazole is an imidazole antifungal that inhibits cytochrome P450dependent lanosterol 14-demethylase, a key enzyme in ergosterol biosynthesis. Unlike many azoles, bifonazole also inhibits additional steps in sterol synthesis, giving it a broader effect on fungal membrane integrity.
Benefits and advantages
Used in dermatology research, antifungal drug-development studies, ergosterol-pathway modelling, membrane-permeability assays and imidazole SAR investigations. Effective against dermatophytes, yeasts and moulds, making it useful in wide-spectrum testing.
Side effects and risks
Possible risks include local irritation, erythema, burning sensation and hypersensitivity. Handle with antifungal-compound PPE.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C22H18N2O |
|---|---|
| Molecular Weight | 310.4 g/mol |
| CAS Number | 60628-96-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 2.45e-03 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | bifonazole; 60628-96-8; Mycospor; Trifonazole; Bifonazol |
| IUPAC/Chemical Name | 1-[phenyl-(4-phenylphenyl)methyl]imidazole |
| InChl Key | OCAPBUJLXMYKEJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H |
| References |
3D Conformer.
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