BENPROPERINE PHOSPHATE
Benproperine phosphate is an antitussive reducing cough reflex sensitivity. Benefits include effective suppression of nonproductive cough. Side effects include drowsiness, dizziness, and dry mouth.
About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Benproperine is an antitussive agent that suppresses the cough reflex by modulating central cough pathways and peripheral vagal afferents. Its exact mechanism is not fully defined but involves depression of the medullary cough centre.
Benefits and advantages
Used in respiratory neurophysiology, cough-reflex pathway research, vagal-afferent modulation studies and antitussive SAR investigations. Serves as a model compound for comparative cough-suppression testing.
Side effects and risks
Risks include dizziness, mild sedation, GI discomfort and rare CNS effects. Handle with respiratory-active compound precautions.
Datasheet
| Molecular Formula | C21H30NO5P |
|---|---|
| Molecular Weight | 407.4 g/mol |
| CAS Number | 19428-14-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | benproperine phosphate; 19428-14-9; Pirexyl; Benproperine trihydrogen phosphate; S831Z48C5W |
| IUPAC/Chemical Name | 1-[1-(2-benzylphenoxy)propan-2-yl]piperidine;phosphoric acid |
| InChl Key | MCVUURBOSHQXMK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H27NO.H3O4P/c1-18(22-14-8-3-9-15-22)17-23-21-13-7-6-12-20(21)16-19-10-4-2-5-11-19;1-5(2,3)4/h2,4-7,10-13,18H,3,8-9,14-17H2,1H3;(H3,1,2,3,4) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.


