BENPROPERINE PHOSPHATE

Benproperine phosphate is an antitussive reducing cough reflex sensitivity. Benefits include effective suppression of nonproductive cough. Side effects include drowsiness, dizziness, and dry mouth.

SKU: 76798d6702d6 Category: Tag:

Product Description


Mechanism of action

Benproperine is an antitussive agent that suppresses the cough reflex by modulating central cough pathways and peripheral vagal afferents. Its exact mechanism is not fully defined but involves depression of the medullary cough centre.

Benefits and advantages

Used in respiratory neurophysiology, cough-reflex pathway research, vagal-afferent modulation studies and antitussive SAR investigations. Serves as a model compound for comparative cough-suppression testing.

Side effects and risks

Risks include dizziness, mild sedation, GI discomfort and rare CNS effects. Handle with respiratory-active compound precautions.

Datasheet


Molecular Formula

C21H30NO5P

Molecular Weight

407.4 g/mol

CAS Number

19428-14-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

benproperine phosphate; 19428-14-9; Pirexyl; Benproperine trihydrogen phosphate; S831Z48C5W

IUPAC/Chemical Name

1-[1-(2-benzylphenoxy)propan-2-yl]piperidine;phosphoric acid

InChl Key

MCVUURBOSHQXMK-UHFFFAOYSA-N

InChl Code

InChI=1S/C21H27NO.H3O4P/c1-18(22-14-8-3-9-15-22)17-23-21-13-7-6-12-20(21)16-19-10-4-2-5-11-19;1-5(2,3)4/h2,4-7,10-13,18H,3,8-9,14-17H2,1H3;(H3,1,2,3,4)

References

https://pubchem.ncbi.nlm.nih.gov/compound/167811;

3D Conformer.

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