BENOXINATE HYDROCHLORIDE
Benoxinate hydrochloride is a topical anesthetic used in ophthalmology to numb the cornea. Benefits include rapid onset. Side effects include temporary stinging and rare allergic reactions. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Benoxinate HCl is an ester-type local anaesthetic that blocks voltage-gated sodium channels in sensory nerves, preventing action potential initiation and propagation. It is primarily used in ophthalmic anaesthesia.
Benefits and advantages
Used in ocular pharmacology, corneal nerve-mapping studies, anaesthetic penetration research and sodium-channel physiology experiments. Its rapid onset makes it useful for short-duration sensory-block modelling.
Side effects and risks
Risks include corneal irritation, allergic reactions, CNS toxicity upon systemic absorption and potential cardiac depression at high exposure levels. Handle under local-anaesthetic safety protocols.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C17H29ClN2O3 |
|---|---|
| Molecular Weight | 344.9 g/mol |
| CAS Number | 5987-82-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Very soluble (hydrochloride salt) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Benoxinate hydrochloride; 5987-82-6; oxybuprocaine hydrochloride; Oxybuprocaine HCL; Benoxinate HCL |
| IUPAC/Chemical Name | 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate;hydrochloride |
| InChl Key | PRGUDWLMFLCODA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H |
| References |
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