BENOXINATE HYDROCHLORIDE
Benoxinate hydrochloride is a topical anesthetic used in ophthalmology to numb the cornea. Benefits include rapid onset. Side effects include temporary stinging and rare allergic reactions.
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Product Description
Mechanism of action
Benoxinate HCl is an ester-type local anaesthetic that blocks voltage-gated sodium channels in sensory nerves, preventing action potential initiation and propagation. It is primarily used in ophthalmic anaesthesia.
Benefits and advantages
Used in ocular pharmacology, corneal nerve-mapping studies, anaesthetic penetration research and sodium-channel physiology experiments. Its rapid onset makes it useful for short-duration sensory-block modelling.
Side effects and risks
Risks include corneal irritation, allergic reactions, CNS toxicity upon systemic absorption and potential cardiac depression at high exposure levels. Handle under local-anaesthetic safety protocols.
Datasheet
| Molecular Formula | C17H29ClN2O3 |
|---|---|
| Molecular Weight | 344.9 g/mol |
| CAS Number | 5987-82-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Very soluble (hydrochloride salt) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Benoxinate hydrochloride; 5987-82-6; oxybuprocaine hydrochloride; Oxybuprocaine HCL; Benoxinate HCL |
| IUPAC/Chemical Name | 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate;hydrochloride |
| InChl Key | PRGUDWLMFLCODA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H |
| References |
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