BENETHAMINE PENICILLIN
Benethamine penicillin is a longacting penicillin formulation used for streptococcal infections and prophylaxis. Benefits include sustained antibiotic levels. Side effects include rash, hypersensitivity, and mild GI upset. Only GMP materials will be supplied, logistics all according to GDP.
About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Benethamine penicillin is a long-acting penicillin designed to slowly release benzylpenicillin following intramuscular administration. It inhibits bacterial cell-wall synthesis by binding penicillin-binding proteins, preventing peptidoglycan cross-linking and causing cell lysis in susceptible organisms.
Benefits and advantages
Used in pharmacokinetic modelling of long-acting antibiotic esters, -lactam stability studies, sustained-release formulation research and microbial susceptibility testing. It is important for studying depot-release kinetics.
Side effects and risks
Risks include hypersensitivity reactions, injection-site irritation and rare neurological events with accidental intravascular injection. Handle with -lactam sensitisation precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C31H35N3O4S |
|---|---|
| Molecular Weight | 545.7 g/mol |
| CAS Number | 751-84-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Benethamine penicillin; Benetacil; Benethamine penicillin G; Penicillin G benethamine; 751-84-8 |
| IUPAC/Chemical Name | N-benzyl-2-phenylethanamine;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| InChl Key | JAQPGQYDZJZOIN-LQDWTQKMSA-N |
| InChl Code | InChI=1S/C16H18N2O4S.C15H17N/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-7-14(8-4-1)11-12-16-13-15-9-5-2-6-10-15/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,16H,11-13H2/t11-,12+,14-;/m1./s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
