APRAMYCIN SULFATE
Aprindine is a class Ib antiarrhythmic agent that blocks sodium channels, stabilizing cardiac conduction. It is used for ventricular arrhythmias. Side effects include dizziness, blurred vision, arrhythmias, and GI upset. Only GMP materials will be supplied, logistics all according to GDP.
About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Apramycin sulfate is an aminoglycoside antibiotic that binds to the bacterial 30S ribosomal subunit, inducing misreading of mRNA and interrupting protein synthesis. Its unique bicyclic sugar structure confers activity against multidrugresistant Gramnegative organisms and certain mycoplasma species.
Benefits and advantages
Used in veterinary antimicrobial studies, ribosomal binding research, efflux pump inhibition modelling, and resistance mechanism profiling. Its unusual structure provides comparative insight into aminoglycoside SAR (structureactivity relationships).
Side effects and risks
Risk of nephrotoxicity, ototoxicity, neuromuscular blockade, and GI upset. Requires antimicrobialgrade containment.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H43N5O15S |
|---|---|
| Molecular Weight | 637.7 g/mol |
| CAS Number | 65710-07-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Apramycin sulfate; 65710-07-8; Apramycin sulphate; 8UYL6NAZ3Q; Apralan |
| IUPAC/Chemical Name | (2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol;sulfuric acid |
| InChl Key | WGLYHYWDYPSNPF-RQFIXDHTSA-N |
| InChl Code | InChI=1S/C21H41N5O11.H2O4S/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31;1-5(2,3)4/h5-21,26-32H,2-4,22-25H2,1H3;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11+,12+,13+,14-,15-,16-,17-,18+,19+,20-,21-;/m1./s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
