About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Amrinone (inamrinone) inhibits PDE3, leading to increased intracellular cAMP in cardiac myocytes and vascular smooth muscle. Elevated cAMP enhances Ca²⁺ influx and contractility while simultaneously causing vasodilation.
Benefits and advantages
Important compound in acute heart failure research, myocardial contractility assays and PDE signalling studies. Provides insight into inotrope–vasodilator relationships.
Side effects and risks
Thrombocytopenia, arrhythmias, hypotension and hepatotoxicity. Handling requires cardiac‑active compound controls.
Datasheet
| Molecular Formula | C10H9N3O |
|---|---|
| Molecular Weight | 187.20 g/mol |
| CAS Number | 60719-84-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 5.60e+00 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | Amrinone; 60719-84-8; inamrinone; Cartonic; Amcoral |
| IUPAC/Chemical Name | 3-amino-5-pyridin-4-yl-1H-pyridin-2-one |
| InChl Key | RNLQIBCLLYYYFJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) |
| References |
3D Conformer.
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