AMPIROXICAM
Ampiroxicam is an NSAID that blocks prostaglandin synthesis. Benefits include reduced pain and inflammation. Side effects include GI upset, dizziness, and edema.
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Product Description
Mechanism of action
Ampiroxicam is a prodrug rapidly converted to piroxicam, a potent COX‑1/COX‑2 inhibitor. Inhibiting prostaglandin synthesis reduces inflammation, pain and fever.
Benefits and advantages
Demonstrates improved GI tolerability and favourable pharmacokinetics compared with piroxicam. Useful in NSAID metabolism research and prodrug activation studies.
Side effects and risks
Risk of GI ulceration, bleeding, renal impairment and hypersensitivity. Handle with NSAID‑grade precautions.
Datasheet
| Molecular Formula | C20H21N3O7S |
|---|---|
| Molecular Weight | 447.5 g/mol |
| CAS Number | 99464-64-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ampiroxicam; 99464-64-9; Flucam; CP 65703; Ampiroxicamum |
| IUPAC/Chemical Name | ethyl 1-[[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1lambda6,2-benzothiazin-4-yl]oxy]ethyl carbonate |
| InChl Key | LSNWBKACGXCGAJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24) |
| References |
3D Conformer.
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